Circular DNA found in cancer cells supports their survival and resistance
Researchers at the University of California, San Diego, have released the findings of a new study that uncovers the role of the circular, 3D shape of extrachromosomal DNA in augmenting mutant oncogenes in cancer cells, resulting in more aggressive tumors with higher resistance to therapy. A paradigm shift in cancer…
Discovery in C. difficile biology opens new window to developing treatments for dangerous infections
A process called sporulation that helps the dangerous bacterium Clostridium difficile (C. difficile) to survive inhospitable conditions and spread is regulated by epigenetics, factors that affect gene expression beyond the DNA genetic code, researchers at the Icahn School of Medicine at Mount Sinai report. This is the first discovery that…