Primaquine Phosphate Tablets BP 7.5mg
Primaquine Phosphate Tablets BP 15mg
Read this carefully before you start taking primaquine and each time you get a refill. This leaflet is a summary and will not tell you everything about this drug. Talk to your healthcare professional about your medical condition and treatment and ask if there is any new information about primaquine.
What is primaquine used for?
Primaquine is used to eliminate certain forms of malaria (specifically Plasmodium vivax and ovale malaria) and help prevent it from coming back.
How does primaquine work?
Primaquine belongs to a group of drugs called the antimalarials. It is used to treat malaria in an infected person. affects the parasite that causes malaria, causing it to die. This stops the infection from continuing.
What are the ingredients in primaquine?
Medicinal ingredients: Primaquine phosphate USP 26.3 mg (equivalent to Primaquine base 15 mg).
Non-medicinal ingredients: carnauba wax, cellulose (microcrystalline), lactose, magnesium stearate, Opacode Black ink S-1-177003(contains shellac glaze; propylene glycol; N-butyl alcohol; black iron oxide; ethanol and methanol), Opadry white YS-1-7443 (contains hypromellose; polyethene glycol 400; titanium dioxide; and polysorbate 80), polyethene glycol 400, red iron oxide, starch and talc. Gluten and tartrazine-free.
Primaquine comes in the following dosage forms:
Pink, film-coated convex round tablet.
Do not use primaquine if:
? If you are allergic to Primaquine phosphate or any of the ingredients in the product (See What are the ingredients in primaquine)
? If you suffer from a medical condition such as rheumatoid arthritis or lupus erythematosus and if you are acutely ill with systemic disease
? If you are taking or have recently taken quinacrine (another antimalarial drug)
? If you are taking drugs that may damage blood cells or their formation
? If you have a disease called severe G6PD deficiency (also known as favism)
? If you are pregnant
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take primaquine. Talk about any health conditions or problems you may have, including if you:
? Suffer from, or have a family history of G6PD (glucose-6-phosphate dehydrogenase) deficiency or favism. Primaquine must not be used if you have severe G6PD deficiency.
? Suffer from nicotinamide adenine dinucleotide (NADH) methemoglobin reductase deficiency
? Suffer from hemolytic anaemia, a condition in which red blood cells are destroyed and removed from the bloodstream before their normal lifespan is over.
? Are pregnant, planning to become pregnant. You should not become pregnant while receiving treatment with primaquine and for 1 menstrual cycle after stopping.
? Are male and planning to father a child. You should not father a child while receiving primaquine treatment and for 3 months after stopping.
? Are breastfeeding or planning to breastfeed. Breastfeeding should be interrupted or the primaquine treatment should be delayed until the end of breastfeeding.
? Have or have had heart disease, an irregular heartbeat, low levels of magnesium or potassium in your blood, or a resting heart rate below 50 beats per minutes.
Other warnings you should know about:
Because primaquine can cause hemolysis in persons with G6PD deficiency, a screening test must be performed prior to use to rule out such a deficiency.
Stop taking primaquine right away and contact your doctor if you develop signs of hemolytic anaemia which include darkening of the urine, dizziness, confusion, fatigue, light-headedness, or shortness of breath.
Primaquine may cause dizziness; do not drive or operate machinery until you know how the drug affects you.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.
The following may interact with primaquine:
Do not take primaquine if you are taking or if you have recently taken quinacrine.
Primaquine can interact with medications that have an effect on heart rhythm (prolong the QT interval).
How to take primaquine:
Taking primaquine after a meal may help to decrease stomach pain or cramps which are possible side effects of this medication.
Usual dose:
Take primaquine exactly as prescribed by your doctor.
Overdose: If you think you have taken too much primaquine, contact your healthcare professional, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.
Storage:
Store between 15-30?C.
Keep out of reach and sight of children.
7. Manufactured in India by:
TAJ LIFE SCIENCES PVT. LTD.
Unit No. 214, Old Bake House,
Bake House Lane, Fort,
Mumbai-400001
at: Ahmedabad- Gujarat, INDIA.
Ho.NO. +91 8448 444 095
Toll Free Phone: (1800-222-434 / 1800-222-825)
