Patient Information Leaflet:
Cyanocobalamin Injection 1000mcg/ml
Cyanocobalamin Injection 500mcg/ml
Read all of this leaflet carefully before you are given this medicine.
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or nurse.
- In this leaflet, Cyanocobalamin 1000 micrograms/ml Solution for Injection will be called Cyanocobalamin.
In this leaflet:
1.
What Cyanocobalamin is for
2. Before you are given Cyanocobalamin
3. How you will be given Cyanocobalamin
4. Possible side effects
5. How to store Cyanocobalamin
6. Further information.
1. What Cyanocobalamin is for
Cyanocobalamin is a form of Vitamin B12, an essential vitamin that is needed for the production of red blood cells.
Cyanocobalamin is used to prevent and treat certain types of anemia, including Addisonian pernicious anemia, and other kinds of anemia which result from a deficiency of Vitamin B12.
It is also used for a test called the Schilling Test, which measures your ability to absorb Vitamin B12 from the bowel.
2. Before you are given Cyanocobalamin
You should not be given Cyanocobalamin if:
- You are allergic to the active ingredient, cyanocobalamin
- You are allergic to any of the other ingredients of Cyanocobalamin (see section 6.)
- You have a condition called toxic amblyopia (poor vision which may be due to Vitamin B12 deficiency).
If any of the above applies to you talk to your doctor or nurse.
Check with your doctor before being given Cyanocobalamin if:
- You are pregnant, planning to become pregnant or breast-feeding
- You have megaloblastic anemia. This is a blood disorder where you have larger than normal blood cells
Tell your doctor if you are taking any of the following medicines:
- Antibiotics (for treating infections) or antimetabolites (medicines which stop cells dividing, such as mercaptopurine for leukemia), as these treatments may interfere with tests to measure the levels of Vitamin B12 in your blood or urine
- An antibiotic called chloramphenicol, as you may not respond well to Cyanocobalamin
- Oral contraceptives ‘The Pill’
- Any other medicine, including medicines obtained without a prescription.
If any of the above applies to you talk to your doctor or nurse.
Pregnancy and breast-feeding
Cyanocobalamin should not be used in pregnancy for treating a kind of anemia called megaloblastic anemia unless you also have a Vitamin B12 deficiency.
Cyanocobalamin is found in breast-milk but it is unlikely that it will harm your baby.
If you are pregnant, trying to become pregnant or are breast-feeding, ask your doctor or nurse for advice before being given Cyanocobalamin.
Driving and using machines
Cyanocobalamin may cause dizziness. If this happens to you, do not drive or use machinery.
3. How you will be given Cyanocobalamin
Important:
Your doctor will choose the dose that is right for you.
You will be given Cyanocobalamin by your doctor or nurse as an injection into a muscle. You may be given it just once or it may be repeated every other day, weekly or monthly, depending on how much your body needs.
Adults and Children
- Treatment of anemia:
- Without neurological (nervous system) involvement: Initially, 250 ? 1000 micrograms, every other day for 1 to 2 weeks, then 250 micrograms weekly until the blood tests are normal.
- Maintenance dose: 1000 micrograms every month.
- With neurological involvement: 1000 micrograms every other day for as long as improvement is noticed.
Maintenance dose: 1000 micrograms every month.
- Prevention of anemia:
- 250 -1000 micrograms every month.
- Schilling Test:
- 1000 micrograms.
Medical check-ups
While you are receiving this medicine, your doctor will want you to have regular blood tests to check your condition. This is to make sure that your medicine is working properly and that the dose you are receiving is right for you.
If you are given more Cyanocobalamin than you should
If you think you have been given too much Cyanocobalamin, you are unlikely to need any special treatment. However, if you suffer any discomfort or side effects you should tell your doctor.
If you have any further questions about the use of this medicine, ask your doctor or nurse.
4. Possible side effects
Like all medicines, Cyanocobalamin can cause side effects, although not everybody gets them.
Stop using Cyanocobalamin and seek immediate medical help if you have an allergic reaction.
This includes any of the following symptoms:
- Difficulties in breathing
- Swelling of your eyelids, face or lips
- Rash or itching especially those covering your whole body
- Collapse.
Effects on the heart and blood
- Low blood potassium levels and irregular heartbeat during the early stages of treatment
- Thrombocytosis (where you have a high number of platelets in your blood)
Effects on the eyes and skin
- Acne-like rash
- Blisters
- Pain at the site of injection
- The skin may become hard at the site of injection
- The skin around the injection site may die.
Effects on the stomach and bowel
- Feeling unwell or sick
Effects on the nervous system
- Dizziness
- Tremor
Other effects
- Fever
- Chills
- Hot flushes
- Pain.
Reporting of side effects
If you get any side effects, talk to your doctor or nurse. This includes any possible side effects not listed in this leaflet. By reporting side effects you can help provide more information on the safety of this medicine.
5. How to store Cyanocobalamin
Keep this medicine out of the sight and reach of children.
Do not use Cyanocobalamin after the expiry date on the label. The expiry date refers to the last day of that month.
Store below 25?C. Keep Cyanocobalamin in the original packaging in order to protect it from light.
Your doctor or nurse will make sure your medicine is correctly stored and disposed of.
6. Further information
What Cyanocobalamin contains
The active substance is cyanocobalamin BP at a strength of 1000 micrograms (1 mg) per ml of solution.
The other ingredients are sodium chloride, acetic acid, and water for injection.
What Cyanocobalamin looks like
Cyanocobalamin 1000 micrograms/ml Solution for Injection is a sterile solution.
It comes in packs of 5 ampoules, each containing 1 ml of solution.
7. Manufactured in India by:
TAJ LIFE SCIENCES PVT. LTD.
Unit No. 214, Old Bake House,
Bake House Lane, Fort,
Mumbai-400001
at: Ahmedabad- Gujarat, INDIA.
Ho.NO.+91 8448 444 095
Toll Free Phone: (1800-222-434 / 1800-222-825)