Betahistine Mesilate Tablet JP 6 mg

Betahistine Mesilate Tablet JP 6 mg
Betahistine Mesilate Tablet JP 12 mg


Betahistine mesilate is an alkylamine. A histamine analogue and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers.

a) Betahistine Mesilate Tablet JP 6mg
Each tablet contains:
Betahistine Mesilate JP            6mg
Excipients                                  q.s.

b) Betahistine Mesilate Tablet JP 12mg
Each tablet contains:
Betahistine Mesilate JP            12mg
Excipients                                  q.s.


This generic drug is indicated in the following cases:

  • Meniere’s disease
  • Prophylactic management of vertigo

Dosage form

Tablet, Oral use.

To be taken with water during meals.

Adults only (> 18 years of age):

-Recommended dose: one to two tablets, three times a day, depending on the individual response.

-Treatment duration: patient to be followed during at least one month, and even longer, if needed, continuously or not.

Children (< 18 years of age): contraindicated.


The following precautions should be taken when administering this drug:

Administer during meals

Drug interactions

Severity: Precaution

Orally administered drugs + Cholestyramine
Risks and Mechanisms Cholestyramine can reduce intestinal absorption, and potentially, the effectiveness of other drugs taken at the same time. This interaction was proved for some substances or therapeutic classes (thyroid hormones, statins, digoxin, oral anticoagulants, hydrochlorothiazide, paracetamol, bile acids) but probably concerns also many other drugs.
Course of Action In general, cholestyramine should be taken sometime after the other drugs (more than two hours, if possible).
Orally administered drugs + Topical gastrointestinal agents, antacids and adsorbents
Risks and Mechanisms Reduced absorption of certain other drugs ingested simultaneously.
Course of Action As a precaution, these topical agents or antacids should be taken some time after any other drug (more than 2 hours, if possible).


Severity: Absolute contraindication

Asthma Hypersensitivity to H1 antihistamines Hypersensitivity to H2 antihistamines Hypersensitivity to one of the components Patients under 18 years old Pheochromocytoma Progressive peptic ulcer


Severity: Precaution

History of peptic ulcer Women of childbearing potential Lactation Pregnancy

Adverse effects

System Medium to high frequency (?1/1 000) Low frequency (<1/1 000) Unknown frequency
Dermatology Exanthema
Digestive system Nausea (Common)
Vomiting (Common)
Abdominal pain
Nervous system Headache (Common) Sleepiness
Other Fatigue
Psychiatry Insomnia


Warnings for special population


This medicine is not recommended for pregnant women unless absolutely necessary. Discuss with your doctor about the potential benefits and risks of this medicine.


This medicine is not recommended for breastfeeding women unless absolutely necessary. Discuss with your doctor about the potential benefits and risks of this medicine.

General warnings

Gastrointestinal disorder

This medicine may increase the risk of stomach ulcers. Inform the doctor if you have a history of peptic ulcer disease or any gastrointestinal disease. Drink adequate amount of water to prevent stomach irritation.


This medicine may increase the risk of breathing problem. Inform the doctor if you have a history of asthma or any lung diseases.

Impaired liver function

Liver injury may cause accumulation of this medicine in the body. Any history of liver disease should be reported to the doctor and necessary precautions should be taken to prevent further accumulation.

Pediatric use

This medicine is not recommended for the children less than 18 years.


All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

  • Monoamine oxidase inhibitors
  • antihistamines
  • Beta-2 agonists

Disease interactions

  • Pheochromocytoma

This medicine is not recommended in patients with a condition called Pheochromocytoma.

Food interactions

Information not available.

Lab interactions

Information not available.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you?re taking.

Side effects

  • Nausea
  • Headache
  • Indigestion
  • Bloating
  • Skin rash
  • Trouble sleeping
  • Fast heartbeat
  • Difficulty in breathing

If overdose is suspected, contact your local poison control centre or emergency room immediately.

Missed dose
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not “double-up” the dose to catch up.

Store at room temperature away from light and moisture. Do not store in the bathroom.

Manufactured in India by:

Unit No. 214, Old Bake House,
Bake House Lane, Fort,
at: Ahmedabad- Gujarat, INDIA.
Ho.NO. +91 8448 444 095
Toll Free Phone: (1800-222-434 / 1800-222-825)